These antifungal preparations contains the active ingredient, Terbinafine which is a broad spectrum antifungal and is effective against skin infections caused by fungus, yeasts and moulds such as ringworm, hots spots and Schnauzer bumps.
It is more effective than other topical antifungals (eg. Clotrimazole and Oxiconazole) because it kills fungus causing the skin infections (fungicidal) and does not just inhibit the growth of fungus (fungistatic). It has shorter duration of treatment in comparison to other topical antifungals.
It is considered to act through inhibition of fungal sterol synthesis. It works by preventing the formation of substances needed by the fungus to grow and develop, which causes weakness and death of the fungus.
Fungi grow rapidly especially in hot and moist weather. Fungal infections affecting pets are most commonly found on the skin, coat and nails. In dogs, about 70% of cases are caused by Microsporum canis, 20% by Microsporum gypseum, and 10% by Trichophyton mentagropphytes; in cats, 98% of cases are caused by Microsporum canis.
Both gel and lotion contain waterproof agent and this antifungal gel does not contain water. Moisture is a risk factor and can promote growth of fungus. The waterproof agent provides water resistance and protects the infected areas.
Penetration enhancers help to promote better absorption and increase bioavailability of the active drug. Enhanced penetration ensures that the active drug reach deeper into infected areas and also ensures higher retention rate of drug.
It also contains ingredient that help to soothe dry flaky skin and promote faster healing.
